A synthetic glycosaminoglycan reduces sinonasal inflammation in a murine model of chronic rhinosinusitis.

A synthetic glycosaminoglycan reduces sinonasal inflammation in a murine model of chronic rhinosinusitis.

Chronic rhinosinusitis (CRS) is characterized by sustained mucosal inflammation, impaired mucociliary clearance, loss of cilia and epithelial barrier breakdown, and tissue remodeling. Certain glycosaminoglycans inhibit various inflammatory mediators, suppress bacterial growth, and provide important...

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Bibliographic Details
Main Authors: Jeremiah A Alt, Won Yong Lee, Brock M Davis, Justin R Savage, Thomas P Kennedy, Glenn D Prestwich, Abigail Pulsipher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6155557?pdf=render

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http://europepmc.org/articles/PMC6155557?pdf=render

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