Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens

Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens

Melioidosis and glanders are multifaceted infections caused by gram-negative bacteria. Here, the authors synthesize a series of oligosaccharides that mimic the lipopolysaccharides present on the pathogens’ surface and use them to develop novel glycoconjugates for vaccine development.

Bibliographic Details
Main Authors: Marielle Tamigney Kenfack, Marcelina Mazur, Teerapat Nualnoi, Teresa L. Shaffer, Abba Ngassimou, Yves Blériot, Jérôme Marrot, Roberta Marchetti, Kitisak Sintiprungrat, Narisara Chantratita, Alba Silipo, Antonio Molinaro, David P. AuCoin, Mary N. Burtnick, Paul J. Brett, Charles Gauthier
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00173-8

Internet

https://doi.org/10.1038/s41467-017-00173-8

Similar Items