MicroRNA miR-308 regulates dMyc through a negative feedback loop in Drosophila

Summary The abundance of Myc protein must be exquisitely controlled to avoid growth abnormalities caused by too much or too little Myc. An intriguing mode of regulation exists in which Myc protein itself leads to reduction in its abundance. We show here that dMyc binds to the miR-308 locus and incre...

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Bibliographic Details
Main Authors: Kaveh Daneshvar, Sritama Nath, Abid Khan, Wesley Shover, Christine Richardson, Julie M. Goodliffe
Format: Article
Language:English
Published: The Company of Biologists 2012-10-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/1/1