Osteopontin-enhanced hepatic metastasis of colorectal cancer cells.

Liver metastasis is a major cause of mortality from colorectal cancer (CRC). However, mechanisms underlying this process are largely unknown. Osteopontin (OPN) is a secreted phosphorylated glycoprotein that is involved in tumor migration and metastasis. The role of OPN in cancer is currently unclear...

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Bibliographic Details
Main Authors: Jianjin Huang, Chi Pan, Hanguang Hu, Shu Zheng, Ling Ding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3480452?pdf=render