A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features

Standard units of measurement are required for a quantitative description of the genome. Here, the authors present a universal synthetic DNA ladder that can measure genetic abundance in next-generation sequencing libraries.

Bibliographic Details
Main Authors: Andre L. M. Reis, Ira W. Deveson, Ted Wong, Bindu Swapna Madala, Chris Barker, James Blackburn, Esteban Marcellin, Tim R. Mercer
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17445-5