Melandrii Herba Extract Attenuates H2O2-Induced Neurotoxicity in Human Neuroblastoma SH-SY5Y Cells and Scopolamine-Induced Memory Impairment in Mice

Melandrii Herba Extract Attenuates H2O2-Induced Neurotoxicity in Human Neuroblastoma SH-SY5Y Cells and Scopolamine-Induced Memory Impairment in Mice

Oxidative stress plays a significant role in the etiology of a variety of neurodegenerative diseases. In this study, we found that Melandrii Herba extract (ME) attenuated oxidative-induced damage in cells. Mechanistically, ME exhibited protection from H2O2-induced neurotoxicity via caspase-3 inactiv...

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Bibliographic Details
Main Authors: Kwang Min Lee, Ae Sin Lee, Inwook Choi
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Molecules
Subjects:
Melandrii Herba extract
neurotoxicity
oxidative stress
scopolamine
cell survival
Online Access:https://www.mdpi.com/1420-3049/22/10/1646

Internet

https://www.mdpi.com/1420-3049/22/10/1646

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