Effect of TNF-Alpha on Caveolin-1 Expression and Insulin Signaling During Adipocyte Differentiation and in Mature Adipocytes

Effect of TNF-Alpha on Caveolin-1 Expression and Insulin Signaling During Adipocyte Differentiation and in Mature Adipocytes

Background/Aims: Tumor necrosis factor-α (TNF-α)-mediated chronic low-grade inflammation of adipose tissue is associated with obesity and insulin resistance. Caveolin-1 (Cav-1) is the central component of adipocyte caveolae and has an essential role in the regulation of insulin signaling. The effect...

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Bibliographic Details
Main Authors: Sara Palacios-Ortega, Maider Varela-Guruceaga, Miriam Algarabel, Fermín Ignacio Milagro, J. Alfredo Martínez, Carlos de Miguel
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Adipogenesis
Insulin receptor
Insulin-stimulated glucose uptake
DNA methylation
3T3-L1
Inflammation
Online Access:http://www.karger.com/Article/FullText/430314

Internet

http://www.karger.com/Article/FullText/430314

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