The design and statistical aspects of VIETNARMS: a strategic post-licensing trial of multiple oral direct-acting antiviral hepatitis C treatment strategies in Vietnam

The design and statistical aspects of VIETNARMS: a strategic post-licensing trial of multiple oral direct-acting antiviral hepatitis C treatment strategies in Vietnam

Abstract Background Eliminating hepatitis C is hampered by the costs of direct-acting antiviral treatment and the need to treat hard-to-reach populations. Access could be widened by shortening or simplifying treatment, but limited research means it is unclear which approaches could achieve sufficien...

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Bibliographic Details
Main Authors: Leanne McCabe, Ian R. White, Nguyen Van Vinh Chau, Eleanor Barnes, Sarah L. Pett, Graham S. Cooke, A. Sarah Walker, on behalf of SEARCH investigators
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Trials
Subjects:
Adaptive design
Bayesian methods
Clinical trial
Hepatitis C
Interim analyses
Multi-arm
Online Access:http://link.springer.com/article/10.1186/s13063-020-04350-x

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http://link.springer.com/article/10.1186/s13063-020-04350-x

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