Transplantation of TAT-Bcl-xL-transduced neural precursor cells: Long-term neuroprotection after stroke

Transplantation of TAT-Bcl-xL-transduced neural precursor cells: Long-term neuroprotection after stroke

Neural precursor cells (NPC) are an interesting tool in experimental stroke research, but their therapeutic potential is limited due to poor long-term survival. We therefore in vitro transduced subventricular zone-(SVZ)-derived NPC with the anti-apoptotic fusion protein TAT-Bcl-xL and analyzed NPC s...

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Bibliographic Details
Main Authors: Thorsten R. Doeppner, Mimount El Aanbouri, Gunnar P.H. Dietz, Jens Weise, Sönke Schwarting, Mathias Bähr
Format: Article
Language:English
Published: Elsevier 2010-10-01
Series:Neurobiology of Disease
Subjects:
Cerebral ischemia
Neural precursor cells
Neurogenesis
Ttroke
TAT-Bcl-xL
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110001956

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http://www.sciencedirect.com/science/article/pii/S0969996110001956

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