GABA and Topiramate Inhibit the Formation of Human Macrophage-Derived Foam Cells by Modulating Cholesterol-Metabolism-Associated Molecules

GABA and Topiramate Inhibit the Formation of Human Macrophage-Derived Foam Cells by Modulating Cholesterol-Metabolism-Associated Molecules

Aims: γ-aminobutyric acid (GABA), the principal inhibitory neurotransmitter, acts on GABA receptors to play an important role in the modulation of macrophage functions. The present study examined the effects of GABA and a GABA receptor agonist on modulating cholesterol-metabolism-associated...

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Bibliographic Details
Main Authors: Ying Yang, Yi-Tian Lian, Shi-Yuan Huang, Yong Yang, Long-Xian Cheng, Kun Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Macrophage
Atherosclerosis
GABA
GABA receptor agonist
Cholesterol
Online Access:http://www.karger.com/Article/FullText/358681

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http://www.karger.com/Article/FullText/358681

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