Genome-wide analysis of regulatory G-quadruplexes affecting gene expression in human cytomegalovirus.

G-quadruplex (G4), formed by repetitive guanosine-rich sequences, is known to play various key regulatory roles in cells. Herpesviruses containing a large double-stranded DNA genome show relatively higher density of G4-forming sequences in their genomes compared to human and mouse. However, it remai...

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Bibliographic Details
Main Authors: Subramaniyam Ravichandran, Young-Eui Kim, Varun Bansal, Ambarnil Ghosh, Jeonghwan Hur, Vinod Kumar Subramani, Subhra Pradhan, Myoung Kyu Lee, Kyeong Kyu Kim, Jin-Hyun Ahn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6179306?pdf=render