Prolonged and severe SARS-CoV-2 infection in patients under B-cell-depleting drug successfully treated: A tailored approach

Prolonged and severe SARS-CoV-2 infection in patients under B-cell-depleting drug successfully treated: A tailored approach

Prolonged B-cell depletion due to anti-CD20 monoclonal antibody (mAbs) therapy impairs the adaptive immune response, causing severe manifestations during COronaVIrus Disease-2019 (COVID-19). The cases of two patients under anti-CD20 therapy who experienced prolonged and severe COVID-19 successfully...

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Bibliographic Details
Main Authors: Alessandra D’Abramo, Serena Vita, Gaetano Maffongelli, Andrea Mariano, Chiara Agrati, Concetta Castilletti, Delia Goletti, Giuseppe Ippolito, Emanuele Nicastri
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:International Journal of Infectious Diseases
Subjects:
Anti-CD20 therapy
SARS-CoV-2 infection
B-cell depletion
Prolonged infection
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971221003805

Internet

http://www.sciencedirect.com/science/article/pii/S1201971221003805

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