Peripheral 5-HT3 Receptors Are Involved in the Antinociceptive Effect of Bunodosine 391

Peripheral 5-HT3 Receptors Are Involved in the Antinociceptive Effect of Bunodosine 391

Bunodosine 391 (BDS 391), a low molecular weight compound isolated from the sea anemone Bunodosoma cangicum, increases the nociceptive threshold and inhibits inflammatory hyperalgesia. Serotonin receptors are involved in those effects. In this study, we have expanded the characterization of the anti...

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Bibliographic Details
Main Authors: Wilson Alves Ferreira Junior, Andre Junqueira Zaharenko, Kohei Kazuma, Gisele Picolo, Vanessa Pacciari Gutierrez, Jose Carlos de Freitas, Katsuhiro Konno, Yara Cury
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Toxins
Subjects:
BDS 391
sea anemone
antinociception
peripheral 5-HT3 receptors
overt pain
neuropathic pain
inflammatory hyperalgesia
Online Access:https://www.mdpi.com/2072-6651/10/1/12

Internet

https://www.mdpi.com/2072-6651/10/1/12

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