Untangling dopamine-adenosine receptor-receptor assembly in experimental parkinsonism in rats

Untangling dopamine-adenosine receptor-receptor assembly in experimental parkinsonism in rats

Parkinson’s disease (PD) is a dopaminergic-related pathology in which functioning of the basal ganglia is altered. It has been postulated that a direct receptor-receptor interaction – i.e. of dopamine D2 receptor (D2R) with adenosine A2A receptor (A2AR) (forming D2R-A2AR oligomers) – finely regulate...

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Bibliographic Details
Main Authors: Víctor Fernández-Dueñas, Jaume J. Taura, Martin Cottet, Maricel Gómez-Soler, Marc López-Cano, Catherine Ledent, Masahiko Watanabe, Eric Trinquet, Jean-Philippe Pin, Rafael Luján, Thierry Durroux, Francisco Ciruela
Format: Article
Language:English
Published: The Company of Biologists 2015-01-01
Series:Disease Models & Mechanisms
Subjects:
Immunoelectron microscopy
Oligomerization
Parkinson’s disease
Proximity ligation assay
TR-FRET
Online Access:http://dmm.biologists.org/content/8/1/57

Internet

http://dmm.biologists.org/content/8/1/57

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