The Bacterium Akkermansia muciniphila: A Sentinel for Gut Permeability and Its Relevance to HIV-Related Inflammation

Gut dysbiosis, namely dysregulation of the intestinal microbiota, and increased gut permeability lead to enhanced inflammation and are commonly seen in chronic conditions such as obesity and aging. In people living with HIV (PLWH), several lines of evidence suggest that a depletion of gut CD4 T-cell...

Full description

Bibliographic Details
Main Authors: Jing Ouyang, John Lin, Stéphane Isnard, Brandon Fombuena, Xiaorong Peng, André Marette, Bertrand Routy, Meriem Messaoudene, Yaokai Chen, Jean-Pierre Routy
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
HIV
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00645/full