Poly(lactic-co-glycolic acid) Nanoparticles Encapsulating the Prenylated Flavonoid, Xanthohumol, Protect Corneal Epithelial Cells from Dry Eye Disease-Associated Oxidative Stress

Poly(lactic-co-glycolic acid) Nanoparticles Encapsulating the Prenylated Flavonoid, Xanthohumol, Protect Corneal Epithelial Cells from Dry Eye Disease-Associated Oxidative Stress

Oxidative stress is a known contributor to the progression of dry eye disease pathophysiology, and previous studies have shown that antioxidant intervention is a promising therapeutic approach to reduce the disease burden and slow disease progression. In this study, we evaluated the pharmacological...

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Bibliographic Details
Main Authors: Anita Kirti Ghosh, Rubina Thapa, Harsh Nilesh Hariani, Michael Volyanyuk, Sean David Ogle, Karoline Anne Orloff, Samatha Ankireddy, Karen Lai, Agnė Žiniauskaitė, Evan Benjamin Stubbs, Giedrius Kalesnykas, Jenni Johanna Hakkarainen, Kelly Ann Langert, Simon Kaja
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
ocular surface disease
dry eye disease
antioxidant
xanthohumol
drug delivery
PLGA nanoparticles
Online Access:https://www.mdpi.com/1999-4923/13/9/1362

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https://www.mdpi.com/1999-4923/13/9/1362

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