Comparative Genomic and Transcriptional Analyses of CRISPR Systems Across the Genus Pyrobaculum

Within the domain Archaea, the CRISPR immune system appears to be nearly ubiquitous based on computational genome analyses. Initial studies in bacteria demonstrated that the CRISPR system targets invading plasmid and viral DNA. Recent experiments in the model archaeon Pyrococcus furiosus uncovered...

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Bibliographic Details
Main Authors: David L Bernick, Courtney L Cox, Patrick P Dennis, Todd M Lowe
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00251/full