Characterising the mechanism of airway smooth muscle β2 adrenoceptor desensitization by rhinovirus infected bronchial epithelial cells.

Characterising the mechanism of airway smooth muscle β2 adrenoceptor desensitization by rhinovirus infected bronchial epithelial cells.

Rhinovirus (RV) infections account for approximately two thirds of all virus-induced asthma exacerbations and often result in an impaired response to β2 agonist therapy. Using an in vitro model of RV infection, we investigated the mechanisms underlying RV-induced β2 adrenoceptor desensitization in p...

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Bibliographic Details
Main Authors: David Van Ly, Alen Faiz, Christine Jenkins, Ben Crossett, Judith L Black, Brent McParland, Janette K Burgess, Brian G G Oliver
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23457497/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23457497/?tool=EBI

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