A systems biology approach identifies molecular networks defining skeletal muscle abnormalities in chronic obstructive pulmonary disease.

Chronic Obstructive Pulmonary Disease (COPD) is an inflammatory process of the lung inducing persistent airflow limitation. Extensive systemic effects, such as skeletal muscle dysfunction, often characterize these patients and severely limit life expectancy. Despite considerable research efforts, th...

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Bibliographic Details
Main Authors: Nil Turan, Susana Kalko, Anna Stincone, Kim Clarke, Ayesha Sabah, Katherine Howlett, S John Curnow, Diego A Rodriguez, Marta Cascante, Laura O'Neill, Stuart Egginton, Josep Roca, Francesco Falciani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21909251/pdf/?tool=EBI