Alpha-tocopherol in intravenous lipid emulsions imparts hepatic protection in a murine model of hepatosteatosis induced by the enteral administration of a parenteral nutrition solution.

Intestinal failure-associated liver disease (IFALD) is a risk of parenteral nutrition (PN)-dependence. Intravenous soybean oil-based parenteral fat can exacerbate the risk of IFALD while intravenous fish oil can minimize its progression, yet the mechanisms by which soybean oil harms and fish oil pro...

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Bibliographic Details
Main Authors: Gillian L Fell, Lorenzo Anez-Bustillos, Duy T Dao, Meredith A Baker, Prathima Nandivada, Bennet S Cho, Amy Pan, Alison A O'Loughlin, Vania Nose, Kathleen M Gura, Mark Puder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217155