The miR-28-5p Targetome Discovery Identified SREBF2 as One of the Mediators of the miR-28-5p Tumor Suppressor Activity in Prostate Cancer Cells

The miR-28-5p Targetome Discovery Identified SREBF2 as One of the Mediators of the miR-28-5p Tumor Suppressor Activity in Prostate Cancer Cells

miR-28-5p is downregulated in some tumor tissues in which it has been demonstrated to have tumor suppressor (TS) activity. Here, we demonstrate that miR-28-5p acts as a TS in prostate cancer (PCa) cells affecting cell proliferation/survival, as well as migration and invasion. Using the miRNA pull ou...

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Bibliographic Details
Main Authors: Sofia Fazio, Gabriele Berti, Francesco Russo, Monica Evangelista, Romina D’Aurizio, Alberto Mercatanti, Marco Pellegrini, Milena Rizzo
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
prostate cancer
mirna targetome
srebf2
mir-28-5p
mirna pull out assay
microrna
Online Access:https://www.mdpi.com/2073-4409/9/2/354

Internet

https://www.mdpi.com/2073-4409/9/2/354

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