High-Resolution Replication Profiles Define the Stochastic Nature of Genome Replication Initiation and Termination

High-Resolution Replication Profiles Define the Stochastic Nature of Genome Replication Initiation and Termination

Eukaryotic genome replication is stochastic, and each cell uses a different cohort of replication origins. We demonstrate that interpreting high-resolution Saccharomyces cerevisiae genome replication data with a mathematical model allows quantification of the stochastic nature of genome replication...

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Bibliographic Details
Main Authors: Michelle Hawkins, Renata Retkute, Carolin A. Müller, Nazan Saner, Tomoyuki U. Tanaka, Alessandro P.S. de Moura, Conrad A. Nieduszynski
Format: Article
Language:English
Published: Elsevier 2013-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713005834

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http://www.sciencedirect.com/science/article/pii/S2211124713005834

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