Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncoprotein E7 of human papillomavirus.

Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncoprotein E7 of human papillomavirus.

Human papillomaviruses (HPVs) are causative agents of various diseases associated with cellular hyperproliferation, including cervical cancer, one of the most prevalent tumors in women. E7 is one of the two HPV-encoded oncoproteins and directs recruitment and subsequent degradation of tumor-suppress...

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Main Authors: Hye-Yeoung Yun, Min Wook Kim, Hye Seon Lee, Wantae Kim, Ji Hye Shin, Hyunmin Kim, Ho-Chul Shin, Hwangseo Park, Byung-Ha Oh, Won Kon Kim, Kwang-Hee Bae, Sang Chul Lee, Eun-Woo Lee, Bonsu Ku, Seung Jun Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000367

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https://doi.org/10.1371/journal.pbio.3000367

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