Reduced expression of Jak-1 and Tyk-2 proteins leads to interferon resistance in Hepatitis C virus replicon

<p>Abstract</p> <p>Background</p> <p>Alpha interferon in combination with ribavirin is the standard therapy for hepatitis C virus infection. Unfortunately, a significant number of patients fail to eradicate their infection with this regimen. The mechanisms of IFN-resist...

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Bibliographic Details
Main Authors: Luftig Ronald, Florman Sander, Garry Robert F, Haque Salima, Taylor Lizeth, Hazari Sidhartha, Regenstein Frederic, Dash Srikanta
Format: Article
Language:English
Published: BMC 2007-09-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/4/1/89