Life cycle analysis of kidney gene expression in male F344 rats.

Age is a predisposing condition for susceptibility to chronic kidney disease and progression as well as acute kidney injury that may arise due to the adverse effects of some drugs. Age-related differences in kidney biology, therefore, are a key concern in understanding drug safety and disease progre...

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Bibliographic Details
Main Authors: Joshua C Kwekel, Varsha G Desai, Carrie L Moland, Vikrant Vijay, James C Fuscoe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3792073?pdf=render