Spectrum-Wide Exploration of Human Adenoviruses for Breast Cancer Therapy

Spectrum-Wide Exploration of Human Adenoviruses for Breast Cancer Therapy

Oncolytic adenoviruses (Ads) are promising tools for cancer therapeutics. However, most Ad-based therapies utilize Ad type 5 (Ad5), which displays unsatisfying efficiency in clinical trials, partly due to the low expression levels of its primary coxsackievirus and adenovirus receptor (CAR) on tumor...

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Bibliographic Details
Main Authors: Nicolas Mach, Jian Gao, Lukas Schaffarczyk, Sebastian Janz, Eric Ehrke-Schulz, Thomas Dittmar, Anja Ehrhardt, Wenli Zhang
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
adenovirus
adenovirus receptors
breast cancer
broad spectrum
cellular entry
high-throughput screening
Online Access:https://www.mdpi.com/2072-6694/12/6/1403

Internet

https://www.mdpi.com/2072-6694/12/6/1403

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