The study to understand the genetics of the acute response to metformin and glipizide in humans (SUGAR-MGH): design of a pharmacogenetic resource for type 2 diabetes.

The study to understand the genetics of the acute response to metformin and glipizide in humans (SUGAR-MGH): design of a pharmacogenetic resource for type 2 diabetes.

Genome-wide association studies have uncovered a large number of genetic variants associated with type 2 diabetes or related phenotypes. In many cases the causal gene or polymorphism has not been identified, and its impact on response to anti-hyperglycemic medications is unknown. The Study to Unders...

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Bibliographic Details
Main Authors: Geoffrey A Walford, Natalia Colomo, Jennifer N Todd, Liana K Billings, Marlene Fernandez, Bindu Chamarthi, A Sofia Warner, Jaclyn Davis, Katherine R Littleton, Alicia M Hernandez, Rebecca R Fanelli, Amelia Lanier, Corinne Barbato, Rachel J Ackerman, Sabina Q Khan, Rosa Bui, Laurel Garber, Elliot S Stolerman, Allan F Moore, Chunmei Huang, Varinderpal Kaur, Maegan Harden, Andrew Taylor, Ling Chen, Alisa K Manning, Paul Huang, Deborah Wexler, Rita M McCarthy, Janet Lo, Melissa K Thomas, Richard W Grant, Allison Goldfine, Margo S Hudson, Jose C Florez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4374872?pdf=render

Internet

http://europepmc.org/articles/PMC4374872?pdf=render

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