Fatal Myelotoxicity Following Palliative Chemotherapy With Cisplatin and Gemcitabine in a Patient With Stage IV Cholangiocarcinoma Linked to Post Mortem Diagnosis of Fanconi Anemia

Fatal Myelotoxicity Following Palliative Chemotherapy With Cisplatin and Gemcitabine in a Patient With Stage IV Cholangiocarcinoma Linked to Post Mortem Diagnosis of Fanconi Anemia

Unrecognized genome instability syndromes can potentially impede the rational treatment of cancer in rare patients. Identification of cancer patients with a hereditary condition is a compelling necessity for oncologists, giving varying hypersensitivities to various chemotherapeutic agents or radiati...

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Bibliographic Details
Main Authors: Nils W. Engel, Simon Schliffke, Ulrich Schüller, Christian Frenzel, Carsten Bokemeyer, Christian Kubisch, Davor Lessel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Oncology
Subjects:
fanconi anemia
FANCA
cholangiocarcinoma
genomic instability
myelotoxicity
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00420/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00420/full

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