A pilot study of the effects of pioglitazone and rosiglitazone on de novo lipogenesis in type 2 diabetes

Treatment of type 2 diabetes mellitus (T2DM) patients with pioglitazone results in a more favorable lipid profile, and perhaps more favorable cardiac outcomes, than treatment with rosiglitazone. Pioglitazone treatment increases VLDL-triacylglycerol clearance, but the role of de novo lipogenesis (DNL...

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Bibliographic Details
Main Authors: Carine Beysen, Elizabeth J. Murphy, Hirisadarahally Nagaraja, Martin Decaris, Timothy Riiff, Alex Fong, Marc K. Hellerstein, Patrick J. Boyle
Format: Article
Language:English
Published: Elsevier 2008-12-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752034596X