Perforin rapidly induces plasma membrane phospholipid flip-flop.

Perforin rapidly induces plasma membrane phospholipid flip-flop.

The cytotoxic cell granule secretory pathway is essential for host defense. This pathway is fundamentally a form of intracellular protein delivery where granule proteases (granzymes) from cytotoxic lymphocytes are thought to diffuse through barrel stave pores generated in the plasma membrane of the...

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Bibliographic Details
Main Authors: Sunil S Metkar, Baikun Wang, Elena Catalan, Gregor Anderluh, Robert J C Gilbert, Julian Pardo, Christopher J Froelich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3171411?pdf=render

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http://europepmc.org/articles/PMC3171411?pdf=render

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