Synthesis of novel 4H-1,2,4-triazole-3-thiol derivatives with 2-(2,6-dichlorophenylamino)benzyl fragment in molecules and their anti-inflammatory activity

Synthesis of novel 4H-1,2,4-triazole-3-thiol derivatives with 2-(2,6-dichlorophenylamino)benzyl fragment in molecules and their anti-inflammatory activity

Aim. The study of anti-inflammatory activity of novel 4H-1,2,4-triazole-3-thiol derivatives is one of the most priority direction of pharmacological investigation of mentioned heterocyclic system. Methods and results. Based on the heterocyclization reaction of N-substituted thiosemicarbazides i...

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Bibliographic Details
Main Authors: Yu. L. Shepeta, M. I. Lelyukh, B. S. Zimenkovsky, R. B. Lesyk
Format: Article
Language:English
Published: Zaporozhye State Medical University 2016-04-01
Series:Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
Subjects:
4H-1 2 4-triazole
Diclofenac
Alkylation
Anti-Inflammatory Agents
Online Access:http://pharmed.zsmu.edu.ua/article/view/61103/58053

Internet

http://pharmed.zsmu.edu.ua/article/view/61103/58053

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