Beauty is in the eye of the beholder: proteins can recognize binding sites of homologous proteins in more than one way.

Understanding the mechanisms of protein-protein interaction is a fundamental problem with many practical applications. The fact that different proteins can bind similar partners suggests that convergently evolved binding interfaces are reused in different complexes. A set of protein complexes compos...

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Bibliographic Details
Main Author: Juliette Martin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2887470?pdf=render