Tributyltin(IV) Butyrate: A Novel Epigenetic Modifier with ER Stress- and Apoptosis-Inducing Properties in Colon Cancer Cells

Tributyltin(IV) Butyrate: A Novel Epigenetic Modifier with ER Stress- and Apoptosis-Inducing Properties in Colon Cancer Cells

Organotin(IV) compounds are a class of non-platinum metallo-conjugates exhibiting antitumor activity. The effects of different organotin types has been related to several mechanisms, including their ability to modify acetylation protein status and to promote apoptosis. Here, we focus on triorganotin...

Full description

Bibliographic Details
Main Authors: Michela Giuliano, Claudia Pellerito, Adriana Celesia, Tiziana Fiore, Sonia Emanuele
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
triorganotin(IV) butyrates
colon cancer
histone acetylation
apoptosis
ER stress
HDAC inhibitors
Online Access:https://www.mdpi.com/1420-3049/26/16/5010

Internet

https://www.mdpi.com/1420-3049/26/16/5010

Similar Items