Statistical modeling of STR capillary electrophoresis signal

Abstract Background In order to isolate an individual’s genotype from a sample of biological material, most laboratories use PCR and Capillary Electrophoresis (CE) to construct a genetic profile based on polymorphic loci known as Short Tandem Repeats (STRs). The resulting profile consists of CE sign...

Full description

Bibliographic Details
Main Authors: Slim Karkar, Lauren E. Alfonse, Catherine M. Grgicak, Desmond S. Lun
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-019-3074-0