Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1.
The target of rapamycin (TOR) kinase coordinately regulates fundamental metabolic and cellular processes to support growth, proliferation, survival, and differentiation, and consequently it has been proposed as a therapeutic target for the treatment of cancer, metabolic disease, and aging. The TOR k...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-03-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC2650726?pdf=render |