The DNA repair gene APE1 T1349G polymorphism and risk of gastric cancer in a Chinese population.

BACKGROUND: Apurinic/apyrimidinic endonuclease 1 (APE1) has a central role in the repair of apurinic apyrimidic sites through both its endonuclease and its phosphodiesterase activities. A common APE1 polymorphism, T1349G (rs3136820), was previously shown to be associated with the risk of cancers. OB...

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Bibliographic Details
Main Authors: Dongying Gu, Meilin Wang, Shizhi Wang, Zhengdong Zhang, Jinfei Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3242764?pdf=render