Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes.
Angiotensin-(1-12) [Ang-(1-12)] functions as an endogenous substrate for the productions of Ang II and Ang-(1-7) by a non-renin dependent mechanism. This study evaluated whether Ang-(1-12) is incorporated by neonatal cardiac myocytes and the enzymatic pathways of ¹²⁵I-Ang-(1-12) metabolism in the ca...
Main Authors: | Sarfaraz Ahmad, Jasmina Varagic, Brian M Westwood, Mark C Chappell, Carlos M Ferrario |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3018413?pdf=render |
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