Nuclear Factor kappa B is required for the production of infectious human herpesvirus 8 virions

Human herpesvirus 8 (HHV8) infection leads to potent activation of nuclear factor kappa B (NFB) in primary and transformed cells. We used recombinant HHV8 (rKSHV.219) expressing green fluorescent protein under the constitutive cellular promoter elongation factor 2 and red fluorescent protein under...

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Bibliographic Details
Main Authors: Negin N Blattman, Michael eLagunoff, Lawrence eCorey
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Microbiology
Subjects:
hf
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00129/full