Involvement of nitric oxide and prostacyclin in the antihypertensive effect of low-molecular-weight procyanidin rich grape seed extract in male spontaneously hypertensive rats

The aim of this study was to evaluate the involvement of endothelial-relaxing factors as possible antihypertensive mechanism of low-molecular-weight procyanidin rich grape seed extract (LM-GSPE). Thirty 17–20-week-old male spontaneously hypertensive rats (SHR) were administered water or 375 mg/kg LM...

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Bibliographic Details
Main Authors: M. Quiñones, L. Guerrero, S. Fernández-Vallinas, Z. Pons, L. Arola, A. Aleixandre, B. Muguerza
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464613002624