Pioglitazone Ameliorates Renal Ischemia-Reperfusion Injury via Inhibition of NF-κB Activation and Inflammation in Rats

Pioglitazone Ameliorates Renal Ischemia-Reperfusion Injury via Inhibition of NF-κB Activation and Inflammation in Rats

Renal ischemia-reperfusion injury (IRI) is considered as a major cause of acute kidney injury. In this study, we investigated the role of the NF-κB signaling pathway and inflammation in the amelioration of renal IRI using pioglitazone. Sprague–Dawley (SD) rats were subjected to bilateral renal arter...

Full description

Bibliographic Details
Main Authors: Gaode Zou, Zhiyu Zhou, Xiaoqing Xi, Ruizhen Huang, Honglin Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Physiology
Subjects:
pioglitazone
renal ischemia-reperfusion injury
NF-κB signaling pathway
inflammation
protective effect
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.707344/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.707344/full

Similar Items