Transcriptomic Changes in Endothelial Cells Triggered by Na,K-ATPase Inhibition: A Search for Upstream Na<sup>+</sup><sub>i</sub>/K<sup>+</sup><sub>i</sub> Sensitive Genes

Transcriptomic Changes in Endothelial Cells Triggered by Na,K-ATPase Inhibition: A Search for Upstream Na<sup>+</sup><sub>i</sub>/K<sup>+</sup><sub>i</sub> Sensitive Genes

Stimulus-dependent elevation of intracellular Ca<sup>2+</sup> affects gene expression via well-documented calmodulin-mediated signaling pathways. Recently, we found that the addition of extra- and intracellular Ca<sup>2+</sup> chelators increased, rather than decreased, the n...

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Bibliographic Details
Main Authors: Elizaveta A. Klimanova, Svetlana V. Sidorenko, Polina A. Abramicheva, Artem M. Tverskoi, Sergei N. Orlov, Olga D. Lopina
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
endothelial cells
Na
K-ATPase
cardiotonic steroids
[Na<sup>+</sup>]<sub>i</sub>/[K<sup>+</sup>]<sub>i</sub>-ratio
FOS
Online Access:https://www.mdpi.com/1422-0067/21/21/7992

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https://www.mdpi.com/1422-0067/21/21/7992

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