Screening and Evaluation of Deleterious SNPs in APOE Gene of Alzheimer’s Disease
Introduction. Apolipoprotein E (APOE) is an important risk factor for Alzheimer’s disease (AD) and is present in 30–50% of patients who develop late-onset AD. Several single-nucleotide polymorphisms (SNPs) are present in APOE gene which act as the biomarkers for exploring the genetic basis of this d...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
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Series: | Neurology Research International |
Online Access: | http://dx.doi.org/10.1155/2012/480609 |