Screening and Evaluation of Deleterious SNPs in APOE Gene of Alzheimer’s Disease

Introduction. Apolipoprotein E (APOE) is an important risk factor for Alzheimer’s disease (AD) and is present in 30–50% of patients who develop late-onset AD. Several single-nucleotide polymorphisms (SNPs) are present in APOE gene which act as the biomarkers for exploring the genetic basis of this d...

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Bibliographic Details
Main Authors: Tariq Ahmad Masoodi, Sulaiman A. Al Shammari, May N. Al-Muammar, Adel A. Alhamdan
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Neurology Research International
Online Access:http://dx.doi.org/10.1155/2012/480609