Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding
<p/> <p>Background</p> <p>The rate at which fitness declines as an organism's genome accumulates random mutations is an important variable in several evolutionary theories. At an intuitive level, it might seem natural that random mutations should tend to interact synergi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2003-02-01
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| Series: | BMC Evolutionary Biology |
| Subjects: | |
| Online Access: | http://www.biomedcentral.com/1471-2148/3/3 |