Learning-Dependent Dendritic Spine Plasticity Is Reduced in the Aged Mouse Cortex
Aging is accompanied by a progressive decrease in learning and memory function. Synaptic loss, one of the hallmarks of normal aging, likely plays an important role in age-related cognitive decline. But little is known about the impact of advanced age on synaptic plasticity and neuronal function in v...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2020-11-01
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| Series: | Frontiers in Neural Circuits |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fncir.2020.581435/full |