Do endogenous opioids and nitric oxide participate in the anticonvulsant action of dipyrone?

It was previously reported that systemic administration of dipyrone inhibited the tonic component of generalized tonic-clonic seizures in both the electroshock and the audiogenic seizure models. The aim of the present study was to investigate the mechanisms involved in the anticonvulsant action of d...

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Bibliographic Details
Main Authors: G.M.L. Reis, M.C. Doretto, I.D.G. Duarte, M.A.K.F. Tatsuo
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2003-09-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000900018