Do endogenous opioids and nitric oxide participate in the anticonvulsant action of dipyrone?

Do endogenous opioids and nitric oxide participate in the anticonvulsant action of dipyrone?

It was previously reported that systemic administration of dipyrone inhibited the tonic component of generalized tonic-clonic seizures in both the electroshock and the audiogenic seizure models. The aim of the present study was to investigate the mechanisms involved in the anticonvulsant action of d...

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Bibliographic Details
Main Authors:	G.M.L. Reis, M.C. Doretto, I.D.G. Duarte, M.A.K.F. Tatsuo
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2003-09-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Epilepsy Dipyrone Audiogenic seizures Electroshock Nitric oxide Opiates
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000900018

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