MRI DTI and PDFF as Biomarkers for Lower Motor Neuron Degeneration in ALS

MRI DTI and PDFF as Biomarkers for Lower Motor Neuron Degeneration in ALS

ObjectiveTo evaluate the utility of nerve magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), and muscle MRI multi-echo Dixon for assessing lower motor neuron (LMN) degeneration in amyotrophic lateral sclerosis (ALS).MethodsIn this prospective observational cohort study, 14 patients wi...

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Bibliographic Details
Main Authors: Thorsten Lichtenstein, Alina Sprenger, Kilian Weiss, Nils Große Hokamp, David Maintz, Marc Schlamann, Gereon R. Fink, Helmar C. Lehmann, Tobias D. Henning
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Neuroscience
Subjects:
amyotrophic lateral sclerosis
diffusion tensor imaging
proton density fat fraction
neurodegeneration
motor neuron disease
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.682126/full

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https://www.frontiersin.org/articles/10.3389/fnins.2021.682126/full

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