Association between the polymorphisms of angiotensin converting enzyme (Peptidyl-Dipeptidase A) INDEL mutation (I/D) and Angiotensin II type I receptor (A1166C) and breast cancer among post menopausal Egyptian females

Association between the polymorphisms of angiotensin converting enzyme (Peptidyl-Dipeptidase A) INDEL mutation (I/D) and Angiotensin II type I receptor (A1166C) and breast cancer among post menopausal Egyptian females

Renin angiotensin system (RAS) is involved in the regulation of cardiovascular homeostasis. Angiotensin (Ang II) is converted from angiotensin I via angiotensin converting enzyme (ACE). Ang II exerts its effects by binding to two types of receptors; AT1R and AT2R. Ang II effect on AT1R promotes prol...

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Bibliographic Details
Main Authors: Rania Mohamed El Sharkawy, Ahmed Mohamed Zaki, Amal Abd El Fattah Kamel, Rania Nabil Bedair, Ahmed Saad Ahmed
Format: Article
Language:English
Published: Taylor & Francis Group 2014-09-01
Series:Alexandria Journal of Medicine
Subjects:
Breast neoplasm
INDEL mutation
Renin-angiotensin system
Peptidyl-Dipeptidase A
Online Access:http://www.sciencedirect.com/science/article/pii/S2090506813000808

Internet

http://www.sciencedirect.com/science/article/pii/S2090506813000808

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