Antivasospastic Effects of Hydroxyfasudil, a Rho-Kinase Inhibitor, After Subarachnoid Hemorrhage

Antivasospastic Effects of Hydroxyfasudil, a Rho-Kinase Inhibitor, After Subarachnoid Hemorrhage

We investigated the anti-vasospastic potential of fasudil’s active metabolite, hydroxyfasudil, a Rho-kinase inhibitor, after subarachnoid hemorrhage (SAH) and also its effect on hemorheological abnormalities following cerebral ischemia. Chronic cerebral vasospasm was produced using a two-hemorrhage...

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Bibliographic Details
Main Authors: Shin-ichi Satoh, Masakazu Takayasu, Koh Kawasaki, Ichiro Ikegaki, Asako Hitomi, Kazuo Yano, Masato Shibuya, Toshio Asano
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319306024

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http://www.sciencedirect.com/science/article/pii/S1347861319306024

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