Inhibition of PI3K increases oxaliplatin sensitivity in cholangiocarcinoma cells

<p>Abstract</p> <p>Background</p> <p>Resistance of cholangiocarcinoma to chemotherapy is a major problem in cancer treatment. The mechanism of resistance is believed to involve phosphoinositide-3- kinase (PI3K)/Akt activation. Although the platinum-containing compound o...

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Bibliographic Details
Main Authors: Udomchaiprasertkul Wandee, Narong Siriluck, Leelawat Kawin, Leelawat Surang, Tungpradubkul Sumalee
Format: Article
Language:English
Published: BMC 2009-01-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/9/1/3