Inhibition of PI3K increases oxaliplatin sensitivity in cholangiocarcinoma cells
<p>Abstract</p> <p>Background</p> <p>Resistance of cholangiocarcinoma to chemotherapy is a major problem in cancer treatment. The mechanism of resistance is believed to involve phosphoinositide-3- kinase (PI3K)/Akt activation. Although the platinum-containing compound o...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-01-01
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Series: | Cancer Cell International |
Online Access: | http://www.cancerci.com/content/9/1/3 |